Publications

Lab Publications

Full PDF List here

2021

	Yang, H., W.A. Bullock, A. Myhal, D. Duffy, P. DeShield, Main, R.P.. Cancellous and cortical gene expression are regulated by the same mechanical load threshold governing the skeletal structural response in the mouse tibia. JBMR Plus 5: e10489. 2021. https://doi.org/10.1002/jbm4.10489 PDF

	Kumar, R. A.K. Tiwari, D. Tripathi, R.P. Main, N. Kumar, P. Sihota, S. Ambwani, N.N. Sharma. Anatomical variations in cortical bone surface permeability: Tibia versus femur. Journal of the Mechanical Behavior of Biomedical Materials 113: 104122. 2021. https://doi.org/10.1016/j.jmbbm.2020.104122 PDF


2020
	Willie, B.M., E. Zimmermann, I. Vitienes, R.P. Main, S.V. Komarova. Bone adaptation: safety factors and load predictability in shaping skeletal form. Bone 131: 115114. 2020. PDF 

	Main, R.P., L.B. Meakin, S.J. Shefelbine, M.J. Silva, M.C.H. van der Meulen, B.M. Willie. The murine tibial loading model: Implementing the model and reporting results. Journal of Orthopaedic Research 38: 233-252. 2020.  doi 10.1002/jor.24466. PDF

	Lescun, T.B., S.B. Adams, S. Chandrasekar, R.P. Main, E.A. Nauman, G.J. Breur. Finite element analysis of seven transcortical pin parameters and their effect on bone-pin interface stresses in the equine third metacarpal bone. Veterinary and Comparative Orthopaedics and Traumatology 33: 121-129. 2020. PDF
-	March 2020 Issue cover. 

	Mundy, L.N., T.B. Lescun, R.P. Main, T.H. Griffin. Insertional characteristics of three different transfixiation pin taps in equine cadaver third metacarpal bones. American Journal of Veterinary Research 81: 172-179. 2020.  PDF

	
2019
	Kuehn, A.L, A.H. Lee, R.P. Main, E.L.R. Simons*. The effects of growth rate and biomechanical loading on bone laminarity within the emu skeleton. PeerJ 7: e7616. 2019. PDF
	Yang, H., X. Xu, W.A. Bullock, R.P. Main. Adaptive changes in micromechanical environments of 
cancellous and cortical bone in response to in vivo loading and disuse. Journal of Biomechanics 89: 85-94. 2019. PDF

2017
	Worke, L.J., J.E. Barthold, B. Seelbinder, T. Novak, R.P. Main, S.L. Harbin, C.P. Neu. Densification of type I collagen matrices as a model for cardiac fibrosis. Advanced Healthcare Materials 1700114. 2017. PDF

	Adams, M.K., T.B. Lescun, A.S. Mechem, W.R. Johnson, T.H. Griffin, R.P. Main. Comparison of insertion characteristics of tapered and cylindrical transfixation pins in equine third metacarpal bone. American Journal of Veterinary Research 78: 1200-1209. 2017. PDF

	Main, R.P. Review: Osteocytes and the bone lacunar-canalicular system: Insights into bone biology and skeletal function using bone tissue microstructure. International Journal of Paleopathology 18: 44-46. 2017. PDF

	Yang, H., R.E. Embry, R.P. Main. Effects of loading duration and rest insertion on cancellous and cortical bone adaptation in the mouse tibia. PLoS ONE 12: e0169519. 2017. PDF

2016
	Verner, K.A., M. Lehner, L.P. Lamas, R.P. Main. Experimental tests of planar strain theory for predicting bone cross-sectional longitudinal and shear strain. Journal of Experimental Biology, 219: 3082-3090. 2016. PDF

	Jun, B.H., M. Giarra, H. Yang, R. Main, P.P. Vlachos. Nanoparticale flow velocimetry with image phase correlation for confocal laser scanning microscopy. Measurement Science and Technology, 27: 104003. 2016. PDF

	Yang, H., M. Lehner, G.M. Adam, T.W. Moore, R.M. Packer, N.E. Lambrechts, R.P. Main. Biomechanical evaluation of two ventral surgical approaches for intervertebral disc decompression in the canine cervical spine. American Journal of Veterinary Research, 77: 846-853. 2016. PDF

	Byrd, C.J., R.P. Main, M.M. Makagon. Evaluating Pekin duck walking ability using a treadmill performance test. Poultry Science, 95: 2244-2249. 2016. PDF

2015
	Duffy, D.J., R.P. Main, G.E. Moore, G.J. Breur, R.P. Millard. Ex vivo biomechanical comparison of barbed suture and standard polypropylene suture for acute tendon laceration in a canine model. Veterinary and Comparative Orthopaedics and Traumatology, 28: 263-269. 2015. PDF

	Aiello, B.R., J. Iriarte-Diaz, R.W. Blob, M.T. Butcher, M.T. Carrano, N.R. Espinoza, R.P. Main, C.F. Ross.  Tissue-level strain magnitude is encoded in tissue-level bone strain rate and cellular-level fluid flow rate. Proceedings of the Royal Society of London B, 1810: 20150321, 2015. PDF

	Melville, K.M., N.H. Kelly, G. Surita, D.B. Buchalter, J.C. Schimenti, R.P. Main, F.P. Ross, M.C.H. van der Meulen. (2015). Effects of deletion of ER in osteoblast-lineage cells on bone mass and adaptation to mechanical loading differ in female and male mice. Journal of Bone and Mineral Research 30: 1468-1480, 2015. PDF

	Calve, S., A. Ready, C. Huppenbauer, R.P. Main, C.P. Neu. Optical clearing in dense connectives tissues to visualize cellular connectivity in situ. PLoS ONE 10: e0116662, 2015. PDF

2014
	Lamas, L.P. G, R.P. Main, J.R. Hutchinson. Ontogenetic scaling patterns and functional anatomy of the pelvic limb musculature in emus (Dromaius novaehollandiae). PeerJ 2, e716, 2014. PDF

	Yang, H., K.D. Butz, D. Duffy, G.L. Niebur, E.A. Nauman, R.P. Main. Characterization of cancellous and cortical bone strain in the in vivo mouse tibial loading model using microCT-based finite element analysis. Bone 66, 131-139, 2014. PDF

	Main, R.P., M.E. Lynch, and M.C.H. van der Meulen. Load-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female mice. Journal of Experimental Biology 217, 1775-1783, 2014. PDF

	Melville, KM., N.H. Kelly, S.A. Khan, J.C. Schimenti, F.P. Ross, R.P. Main, M.C.H. van der Meulen. Female mice lacking estrogen receptor-alpha in osteoblasts have compromised bone mass and strength. Journal of Bone and Mineral Research 29, 370-379, 2014. PDF

2013
	Willie, B.M., A.I. Birkhold, H. Razi, T. Thiele, M. Aido, B. Kruck, A. Schill, S. Checa, R.P. Main, G.N. Duda. Diminished response to in vivo mechanical loading in trabecular and not cortical bone in adulthood of female C57Bl/6 mice coincides with a reduction in deformation to load. Bone 55, 335-346, 2013. PDF

2011
	Lynch, M.E., R.P. Main, Q. Xu, T.L. Schmicker, M.B. Schaffler, T.M. Wright, M.C.H. van der Meulen. Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging. Bone 49, 439-446, 2011.  authors contributed equally to this work PDF

2010
	Main, R.P., M.E. Lynch, and M.C.H. van der Meulen. In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice. Journal of Biomechanics 43, 2689-2694, 2010. PDF

	Lynch, M.E., R.P. Main, Q. Xu, D.J. Walsh, M.B. Schaffler, T.M. Wright, and M.C.H. van der Meulen. Cancellous bone adaptation to dynamic tibial compression is not sex-dependent in growing mice. Journal of Applied Physiology 109, 685-691, 2010. PDF

2008
	Moreno, C.A., R.P. Main, and A.A. Biewener. Variability in forelimb bone strains during non-steady locomotor activities in goats. Journal of Experimental Biology 211, 1148-1162, 2008. PDF

2007
	Main, R.P. and A.A. Biewener. Skeletal strain patterns and growth in the emu hindlimb during ontogeny. Journal of Experimental Biology 210, 2676-2690, 2007. PDF

	Main, R.P. Ontogenetic relationships between in vivo strain environment, bone histomorphometry, and growth in the goat radius. Journal of Anatomy 210, 272-293, 2007. PDF

2006
	Markey, M.J., R.P. Main, and C.R. Marshall. In vivo cranial suture function and suture morphology in the extant fish Polypterus: implications for inferring skull function in living and fossil fish. Journal of Experimental Biology 209, 2085-2102, 2006. PDF

	Main, R.P. and A.A. Biewener. In vivo bone strain and ontogenetic growth patterns in relation to life history strategies and performance in two vertebrate taxa: goats and emu. Physiological and Biochemical 
Zoology 79 (1), 57-72, 2006. PDF

2005
	Main, R.P., A. de Ricqles, J.R. Horner, and K. Padian. The evolution of thyreophoran dinosaur scutes: implications for plate function in stegosaurs. Paleobiology 31 (2), 291-314, 2005. PDF

2004
	Griffin, T.M., R.P. Main, and C.T. Farley. Biomechanics of quadrupedal walking: how do four-legged animals achieve inverted pendulum-like movements? Journal of Experimental Biology 207, 3545-3558, 2004. PDF

	Main, R.P. and A.A. Biewener. Ontogenetic patterns of limb loading, in vivo bone strains and growth in the goat radius. Journal of Experimental Biology 207, 2577-2588, 2004.PDF